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IgE regulates airway smooth muscle phenotype: Future perspectives in allergic asthma |
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| Authors: | Naresh Singh Redhu Abdelilah S Gounni |
| Affiliation: | Naresh Singh Redhu, Division of GI/Nutrition, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, United StatesAbdelilah S Gounni, Department of Immunology, Faculty of Health Sciences, College of Medicine, University of Manitoba, Winnipeg, MB R3E0T5, Canada |
| Abstract: | The purpose of this commentary is to highlight the emerging role of IgE on airway smooth muscle (ASM) cells function through activation of the high-affinity Fc receptor for IgE. We discuss the potential implications of IgE-mediated ASM sensitization in airway inflammation and remodeling, the hallmark features of allergic asthma. |
| Keywords: | IgE Airway Allergic asthma Remodeling Inflammation |
| 点击此处可从《World Journal of Immunology》浏览原始摘要信息 | |