2002 - 2014年上海市浦东新区居民大肠癌死亡及减寿率分析

目的 了解2002 - 2014年浦东新区居民大肠癌死亡流行病学特点及其趋势，为制定相关的干预措施提供依据。方法 根据2002 - 2014年浦东新区户籍死因监测数据库，采用死亡率、标化死亡率、年度变化百分比(APC) 、潜在减寿年数(PYLL)、平均减寿年数(AYLL)等指标对大肠癌死亡情况进行分析。结果 2002 - 2014年浦东新区大肠癌粗死亡率为21.64/10万，标化死亡率为9.84/10万。大肠癌粗死亡率呈现逐年上升的趋势(APC = 3.99%, Z = - 17.207, P ＜0.001)，标化死亡率无明显变化趋势(APC = 0.34%，Z = - 1.270, P = 0.230)。男性大肠癌死亡率高于女性（Z = 8.286, P ＜0.001）。浦东新区大肠癌PYLL为32 137年，PYLL率为0.93‰，AYLL为4.31年/人。PYLL呈现逐年上升的趋势（APC = 2.26%, Z = - 2.920, P = 0.014）。结论 浦东新区大肠癌粗死亡率及PYLL呈现逐年上升的趋势，提示应加强针对大肠癌的防控措施，深入推进上海市大肠癌筛查工作。

Analysis of the mortality and years of life lost of colorectal cancer among residents in Pudong New Area of Shanghai between 2002 and 2014

Objective The study aimed to assess the epidemiological characteristics and trends of colorectal cancer deaths among residents in Pudong New Area between 2002 and 2014, so as to provide a reference for developing the relevant intervention measures. Methods Data on colorectal cancer deaths among residents in Pudong New Area between 2002 and 2014 were retrieved from the monitoring database of death causes in the Area, and mortality, standardized mortality, annual percent change (APC), potential years of life lost (PYLL), and average years of life lost (AYLL) of the colorectal cancer deaths were analyzed. Results The crude mortality and standardized mortality of colorectal cancer in Pudong New Area between 2002 and 2014 were 21.64/100 000 and 9.84/100 000, respectively. The crude mortality of colorectal cancer had increased over the years (APC=3.99%, Z=-17.207, P＜0.001), while the trend of change in standardized mortality was not significant (APC=0.34%, Z=-1.270, P=0.230). The mortality in males was higher than that in females (Z=8.286, P＜0.001). The PYLL of colorectal cancer in the Area was 32137 years, the PYLL rate was 0.93‰, and the AYLL was 4.31 years per person. The PYLL had increased over the years (APC=2.26%, Z=-2.920, P=0.014). Conclusion The crude mortality and PYLL of colorectal cancer among the residents in Pudong New Area had been rising, suggesting that the prevention and control of colorectal cancer should be strengthened and colorectal cancer screening for Shanghai residents should be further implemented.