平阳霉素碘油乳剂子宫动脉栓塞治疗症状性子宫肌瘤

目的 评价平阳霉素碘油乳剂（Ｐｉｎｙａｎｇｍｙｃｉｎ ｌｉｐｉｏｄｏｌ ｅｍｕｌｓｉｏｎ，ＰＬＥ）子宫动脉灌注对症状性子宫肌瘤的疗效和副作用。方法 对２５例症状性子宫肌瘤患者进行选择性子宫动脉ＰＬＥ灌注，随访３～１８个月，平均６个月，观察术后症状缓解情况和子宫缩小程度。结果 除２例仅完成单侧操作外，其余均治疗成功。子宫肌瘤的动脉造影表现为子宫动脉明显增粗，分支数量增多、纡曲。子宫体增大，染色明显并

Uterine artery embolization with Pingyangmycin lipiodol emulsion for treatment of symptomatic uterine fibroids

Objective To evaluate the effectiveness and side effects of uterine arterial embolization with Pingyangmycin(a homogenous bleomycin) lipiodol emulsion(PLE) for symptomatic uterine fibroids. Methods Uterine arterial embolization with PLE was performed in 25 patients.The improvement of symptoms and uterine size changes were followed up in 3-18 months(mean 6 months) after the procedure. Results All but 2 cases were successfully treated bilaterally.Superselective angiography showed enlargement of uterine artery,accompanied by tortuous branches.The uterine size was increased.The uterus itself was significantly stained and emptied slowly. Coagulation necrosis was found in resected fibroids after embolization in 3 patients. One month after the procedure, a mean 40% reduction of uterine volume was obtained in 18 followed up cases.The clinical symptoms were relieved significantly. The main side effects were hypogastic pain(13/25),which was intense in 6 cases. Conclusion Uterine arterial embolization with PLE is a good non surgical therapy in symptomatic uterine fibroids with mild side effects.