Studies on Lymphocytes. II. The Production of Lymphocytosis by Intravenous Heparin in Calves |
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| Authors: | JANSEN, CORNELIUS R. CRONKITE, EUGENE P. MATHER, GEORGE C. NIELSEN, NIELS O. RAI, KANTI ADAMIK, EMIL R. SIPE, CLYDE R. |
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| Affiliation: | 1 Medical Research Center, Brookhaven National Laboratory, Upton, N. Y.
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| Abstract: | 1. Intravenous commercial heparin produces a lymphocytosis in the calf.The effect is not due to the preservative commonly present in heparin.2. The lymphocytosis is mediated to a great extent by an increased inputof lymphocytes into the blood via the thoracic duct.3. The necessity of considering, plus controlling the heparin effect onblood lymphocyte levels and on the output of thoracic duct lymphocytes inall studies on lymphocyte production, migration and behavior, is discussedand emphasized. Submitted on March 29, 1962 Accepted on June 25, 1962 |
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