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| 职业接触铅工人血细胞参数变化的调查 | |
| 引用本文： | 彭珊茁,张春生,王朝和,魏明至,张杰,郗卓利,杨晓霞.职业接触铅工人血细胞参数变化的调查[J].中华劳动卫生职业病杂志,2002,20(5):334-335. |
| 作者姓名： | 彭珊茁 张春生 王朝和 魏明至 张杰 郗卓利 杨晓霞 |
| 作者单位： | 1. 110024,沈阳市第九人民医院 2. 沈阳市卫生监督所 3. 沈阳市劳动卫生职业病研究所 |
| 摘 要： | 目的 对 5 98名工人的血铅及血细胞参数进行测定 ,以了解职业铅接触对工人造血系统的影响以及血细胞参数的变化。方法 据血铅测定水平将 5 98名职业接触铅工人分为 2组 :铅接触组 (血铅小于 2 .4 1μmol/ /L) 32 5名和铅吸收组 (血铅大于或等于 2 .4 1μmol/L) 2 73名。血铅测定采用石墨炉原子吸收法 ;血细胞参数的测定采用全自动血细胞分析仪进行测定。结果 铅吸收组的血红蛋白 (Hb) 男 :(12 9.3± 12 .3)g/L ,女 :(112 .2± 9.4 )g/L]、红细胞压积 (HCT) 男 :(0 .338± 0 .0 30 )L/L ,女 :(0 .30 2± 0 .0 2 8)L/L]明显低于正常组和铅接触组 ,差异均有显著性 (P <0 .0 5 ,P <0 .0 1) ;并且随血铅水平增高 ,Hb和HCT水平降低 ,血铅与Hb和HCT有弱的负相关关系。铅吸收组的红细胞平均分布宽度 (RDW) (男 :16 .6 8%± 0 .80 % ,女 :16 .98%± 0 .98% )明显高于正常组和铅接触组 ,铅接触组的RDW(男 :14 .77%± 0 .83% ,女 :14 .92 %± 1.13% )也明显高于正常组 ,差异均有显著性 (P <0 .0 5 ,P <0 .0 1) ;血铅与RDW有弱的正相关关系。结论 用Hb、HCT和RDW 3个指标可以反映铅作业工人是否贫血和贫血程度。 |
| 关 键 词： | 血铅 血红蛋白 红细胞压积 红细胞平均分布宽度 贫血 职业性铅中毒 |
| 修稿时间： | 2001年8月3日 |
The investigation on the changes of haematological parameters in the occupationally lead exposed workers |
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| PENG Shanzhuo,ZHANG Chunsheng,WANG Chaohe,WEI Mingzhi,ZHANG Jie,XI Zhuoli,YANG Xiaoxia. Shenyang No.th People's Hospital,Shenyang ,China.The investigation on the changes of haematological parameters in the occupationally lead exposed workers[J].Chinese Journal of Industrial Hygiene and Occupational Diseases,2002,20(5):334-335. | |
| Authors: | PENG Shanzhuo ZHANG Chunsheng WANG Chaohe WEI Mingzhi ZHANG Jie XI Zhuoli YANG Xiaoxia Shenyang Noth People's Hospital Shenyang China |
| Institution: | Shenyang No. 9th People's Hospital, Shenyang 110024, China. |
| Abstract: | OBJECTIVE: To estimate the level of blood lead and some haematological parameters in the workers occupationally exposed to lead so as to know the effect of lead exposure on hematopoietic system in exposed workers. METHODS: The graphite furnace atomic absorption spectrocopy was used to determine blood lead (BPb). The haematological parameters were determined by Sysmex KX-21 automated haematology analyzer. RESULTS: Hemoglobin (Hb) in the lead-absorption groupmale: (129.3 +/- 12.3) g/L, female: (112.2 +/- 9.4) g/L], and hematocrit (HCT) in the lead-absorption groupmale: (0.338 +/- 0.030) L/L, female: (0.302 +/- 0.028) L/L] were significantly lower than those in normal people group and lead-exposed group (P < 0.05, P < 0.01). The relationships between BPb and Hb, HCT were weakly negative correlation. Red cell distribution width (RDW) in the lead-absorption group(male: 16.68% +/- 0.80%, female: 16.98% +/- 0.98%) were significantly higher than those in normal people group and lead exposed group, and RDW in lead exposed group (male: 14.77% +/- 0.83%, female: 14.92% +/- 1.13%) were higher than that in normal people group. BPb was weakly positively correlated with RDW. CONCLUSION: Hb, HCT and RDW were three indices which may reflect the occurrences and degrees of anaemia in lead exposed workers. |
| Keywords: | Blood lead Hemoglobin Hematocrit Red cell distribution width Anemia |
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