| 血管紧张素转化酶2的研究进展 |
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| 引用本文： | 陆蓓莉,吴珑芝. 血管紧张素转化酶2的研究进展[J]. 中国卫生产业, 2013, 0(23): 29-30 |
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| 作者姓名： | 陆蓓莉 吴珑芝 |
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| 作者单位： | [1]上海外国语大学保健中心,上海200083 [2]上海八五医院干部病房,上海200052 |
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| 摘 要： | 血管紧张素转换酶2（ACE2）是肾素血管紧张素系统（RAS）的新成员，是新发现的血管紧张素转换酶（ACE）的相关酶。ACE2的主要作用是降解血管紧张素II（AgnⅡ），生成7肽的血管紧张素-1-7（Agnl-7）。在RAS中，ACE2与ACE可能产生相反的效应。研究发现，ACE2与高血压、心力衰竭、急性呼吸窘迫综合征（ARDS）及肾脏、生殖系统疾病都有密切联系。
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| 关 键 词： | 血管紧张素转换酶2 肾素血管紧张素系统 |
The Progress in angiotensin-converting enzyme 2 research |
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| Affiliation: | LU Beili, WU Longzh(1.Shanghai international studies university health center, Shanghai 200083, China; 2.Shanghai einty-five hospital ward cadres, Shanghai 200052, China) |
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| Abstract: | Angiotensin-converting enzyme 2 is a new member of the reninan-giotensin system.it is a newly discovered peptide- carboxylase related to angiotensin-converting enzyme. The main function of ACE2 is to degrade angiotensin Ⅱ and generate angiotensinl-7. In reninan-angiotensin system, ACE2 and ACE may have opposite balancing functions.It has been showed that ACE2 is closely involved in hypertension, heart failure, ARDS, and disease of kidney and reproductive system. |
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| Keywords: | Angiotensin-converting enzyme 2 Reninan-angiotensin system |
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