参芪扶正注射液对结肠癌化疗患者生活质量影响研究

目的:探讨参芪扶正注射液对结肠癌化疗患者生活质量的影响。方法:纳入初次接受化疗的结肠癌患者126例,随机分为常规化疗组及加用参芪注射液组;采用焦虑自我评定量表(SAS)、抑郁自我评定量表(SDS)及欧洲癌症研究生活质量核心问卷(EORTC QLQ-C30)评定患者生活质量。结果:化疗后两组患生活质量均出现不同程度下降,于化疗后第7d达到高峰,出院前略有好转,但尚未恢复至化疗前水平;与常规化疗组相比,加用参芪注射液组患者生活质量功能及症状各项评分均较高(P<0.05)。结论:在常规化疗基础上加用参芪注射液可提高结肠癌患者生活质量。

Effects of Sanqifuzheng injection on life quality of patients with colon cancer

Objective: To investigate the effects of Sanqifuzheng injection on the life quality of patients with colon cancer.Methods: A total of 126 colon patients were included,which were further divided into control group(received conventional treatment) and Sanqifuzheng injection treatment group(received conventional treatment plus Sanqifuzheng injection).SAS,SDS and EORTC QLQ-C30 were used to assess the life quality of included patients.Results: Life quality was decreased in both group.It was in the poorest status 7 days after chemotherapy,but was improved before discharge.However,life quality was no more comparable with the level before therapy.Compared to conventional group,quality of life of patients in Sanqifuzheng injection treatment group was significantly improved,with significant higher score(P<0.05).Conclusions: Conventional treatment plus Sanqifuzheng injection can improve quality of life of patients with colon cancer.