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| 轻、中度疼痛对第一、第二躯体感觉皮质激活的功能磁共振成像研究 | |
| 引用本文： | 公维义,薛蕴菁,宋施委,张良成,苏建生,范崇玖.轻、中度疼痛对第一、第二躯体感觉皮质激活的功能磁共振成像研究[J].中国康复理论与实践,2012,18(5):423-425. |
| 作者姓名： | 公维义 薛蕴菁 宋施委 张良成 苏建生 范崇玖 |
| 作者单位： | 1. 福建医科大学附属协和医院麻醉科,福建福州市,350001 2. 福建医科大学附属协和医院核磁共振室,福建福州市,350001 3. 福建医科大学附属协和医院神经外科,福建福州市,350001 |
| 基金项目： | 福建省卫生厅青年基金资助项目 |
| 摘 要： | 目的研究轻、中度疼痛电刺激对第一躯体感觉皮质(SⅠ)和第二躯体感觉皮质(SⅡ)的激活规律。方法对7名右利手健康志愿者右足测定痛觉阈值后,给予痛觉阈值和2倍痛觉阈值刺激,进行视觉模拟评分(VAS)和疼痛分级,行功能磁共振成像。结果痛觉阈值和2倍痛觉阈值刺激分别引起志愿者轻度疼痛和中度疼痛;两种刺激均可激活SⅠ和SⅡ,并以左侧为主。其中,轻度疼痛主要激活左侧SⅠ,对两侧SⅡ激活区域小;中度疼痛明显激活左侧SⅠ和双侧SⅡ。结论 SⅠ对轻、中度疼痛电刺激反应一致,但SⅡ对中度疼痛电刺激的反应更为明显。 |
| 关 键 词： | 疼痛 电刺激 躯体感觉皮质 功能磁共振成像 |
Primary and Secondary Somatosensory Cortex Activation Induced by Mild and Moderate Pain:A Functional Magnetic Resonance Imaging Study |
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| Institution: | GONG Wei-yi, XUE Yun-jing, SONG Shi-wei, et al. Department of Anesthesiology, Union Hospital of Fujian Medicine University, Fuzhou 350001, Fujian, China |
| Abstract: | Objective To explore the activation of the primary somatosensory cortex(SⅠ) and secondary somatosensory cortex(SⅡ) under mild and moderate pain.Methods 7 healthy right-handed volunteers accepted electrostimulation of 1 and 2 times pain threshold respectively.The severity of pain was determined with the Visual Analogue Score(VAS),and they received functional magnetic resonance imaging(fMRI) simultaneously.Results 1 and 2 times pain threshold electrical stimulation caused mild and moderate pain respectively.Both mild and moderate pain activated contralateral SⅠ similarly,and bilateral SⅡ with pain intensity.Conclusion SⅠ and SⅡ respond to the mild and moderate pain in different ways. |
| Keywords: | pain electrostimulation somatosensory cortex functional magnetic resonance imaging |
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