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| 早期康复训练对急性脑梗死患者血清脑源性神经营养因子表达及运动功能的影响 | |
| 引用本文： | 甄君,董杰,王雪晴,耿建红,韩蓉蓉. 早期康复训练对急性脑梗死患者血清脑源性神经营养因子表达及运动功能的影响[J]. 中国康复理论与实践, 2012, 18(5): 409-410 |
| 作者姓名： | 甄君 董杰 王雪晴 耿建红 韩蓉蓉 |
| 作者单位： | 1. 中山大学附属第五医院康复医学科,广东珠海市,519000 2. 中山大学附属第五医院心血管科,广东珠海市,519000 3. 中山大学附属第五医院神经内科,广东珠海市,519000 |
| 摘 要： | 目的观察早期康复训练对急性脑梗死患者血清脑源性神经营养因子(BDNF)表达及运动功能的影响。方法 48例急性脑梗死患者随机分为康复组(n=24)和对照组(n=24),对照组仅采用药物治疗,康复组在此基础上进行早期康复训练。分别于治疗前后检测两组患者血清BDNF水平,采用Fugl-Meyer运动功能评定(FMA)评价各组运动功能。结果两组患者治疗后血清BDNF表达及FMA评分均较治疗前增加(P<0.05),康复组优于对照组(P<0.05)。结论早期康复训练有助于促进急性脑梗死患者血清BDNF表达,改善运动功能。 |
| 关 键 词： | 脑梗死 康复 脑源性神经营养因子 运动功能 |
Effect of Early Rehabilitation Training on Serum Brain-derived Neurotrophic Factor Expression and Motor Function in Patients with Acute Cerebral Infarction |
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| Affiliation: | ZHEN Jun, DONG Jie, WANG Xue-qing, et al. Department of Rehabilitation Medicine, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai 519000, Guangdong, China |
| Abstract: | Objective To observe the effects of early rehabilitation training on serum brain-derived neurotrophic factor(BDNF) expression and motor function in patients with acute cerebral infarction.Methods 48 patients with acute cerebral infarction were randomly divided into rehabilitation group(n=24) and control group(n=24).The control group accepted routine medication,while the rehabilitation group accepted early rehabilitation training in addition.They were assessed with Fugl-Meyer Assessment(FMA),and the expression of BDNF in serum was detected before and after treatment.Results The expression of BDNF and the score of FMA increased significantly after treatment in both groups(P<0.05),but increased more in the rehabilitation group than in the control group(P<0.05).Conclusion Early rehabilitation training can promote the expression of serum BDNF and recovery of motor function in patients with acute cerebral infarction. |
| Keywords: | cerebral infarction rehabilitation brain-derived neurotrophic factor motor function |
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