|
|||||
|
|
| 一株携带VanB基因的异质性耐万古霉素表皮葡萄球菌的发现 | |
| 引用本文： | 谢忆虹,彭梅,糜祖煌,万唐,龚金莲,余方友,王涛. 一株携带VanB基因的异质性耐万古霉素表皮葡萄球菌的发现[J]. 中国医院药学杂志, 2006, 26(5): 582-585 |
| 作者姓名： | 谢忆虹 彭梅 糜祖煌 万唐 龚金莲 余方友 王涛 |
| 作者单位： | 1. 南昌市第一医院,江西,南昌,330008 2. 无锡市克隆遗传技术研究所,江苏,无锡,214026 3. 温州医学院附属第一医院,浙江,温州,325000 4. 广州中山大学达安基因诊断中心,广东,广州,510665 |
| 基金项目： | 江西省卫生厅重大招标课题(项目编号:200101) |
| 摘 要： | 目的:利用NCCLS推荐的菌群分析法对南昌地区收集到的耐甲氧西林葡萄球菌(MRS)进行异质性耐万古霉素葡萄球菌的筛查,并对筛查到的菌株进行耐药基因检测和病案回顾性分析。方法:利用NCCLS推荐的菌群分析法进行异质性耐万古霉素菌株的筛查;利用聚合物酶链反应PCR法进行耐万古霉素VanA、VanB、VanC1、VanC2/3检测。结果:从一位患者的褥疮分泌物中分离到的一株异质性耐万古霉素葡萄球菌(代号H40)并检测出了耐万古霉素VanB基因。本研究中所测得的VanB基因序列已登录于NCBI,登录号为:AY960704。结论:异质性耐万古霉素葡萄球菌中检出VanB基因应属首例。 |
| 关 键 词： | 葡萄球菌 万古霉素 耐药 基因 |
| 文章编号： | 1001-5213(2006)05-0582-04 |
| 收稿时间： | 2006-01-23 |
| 修稿时间： | 2006-01-23 |
The discovery of a hetero-vacomycin-resistant stapylococcus epidermidis carrying the gene of VanB |
|
| XIE Yi-hong,PENG Mei,MI Zu-huang,WANG Tang,GONG Jin-lian,YU Fang-you,WANG Tao. The discovery of a hetero-vacomycin-resistant stapylococcus epidermidis carrying the gene of VanB[J]. Chinese Journal of Hospital Pharmacy, 2006, 26(5): 582-585 | |
| Authors: | XIE Yi-hong PENG Mei MI Zu-huang WANG Tang GONG Jin-lian YU Fang-you WANG Tao |
| Affiliation: | 1. The First Hospital of Nanchang City, Jiangxi Nanchang 330008, China; 2. Wuxi Research Institute of Clone Technology, Jiangsu Wuxi 214026,China; 3. The First Affiliated Hospital of Wenzhou Medical College, Zhejiang Wenahou 325000,China; 4. Anta Gene-Diagnosis Center of Zhongshan University, Guangdong Guangzhou 510665,China |
| Abstract: | OBJECTIVE The NCCLS recommended bacterium group analysis was adopted to look for hetero-vacomycin-resistant stapylococci MRS separated from the symptoms of several hospitals were applied in the experiment.The medicine-resisting-gene of selected bacterium was tested and a reviewing analysis was made of cases.METHODS The NCCLS recommended bacterium group analysis was adopted to look for vari-vancomycin-resisting bacterium;PCR method was used to test vari-vancomycin-resisting VanA,VanB,VanC_1,VanC2/3.RESULTS The vancomycin-resisting gene of VanB was found in a hetero-vacomycin-resistant stapylococci(code: H40) from a patient's bedsore secretion.The found gene of VanB was registered in NCBI,and the serial number was AY960704.CONCLUSION The gene of VanB was found from vari-vancomycin-resisting staphylococcus is the first case in our country. |
| Keywords: | staphylococcus vancomycin medicine-resisting gene |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |