^a Department of Neurology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA

^b Bioinformatics Program, 48 Cummington Street, Boston University, Boston, USA

^c Laboratory of Genome Structure Analysis, Human Genome Center, the Institute of Medical Science, the University of Tokyo, 4-6-1, Shirokanedai, Minatoku, Tokyo 108-8639, Japan

^d Department of Anesthesia, Massachusetts General Hospital and Harvard Medical School, 149 MGH East, 13th Street, Charlestown, MA 02129, USA

^e Department of Neurology, Massachusetts General Hospital and Harvard Medical School, 149 MGH East, 13th Street, Charlestown, MA 02129, USA

^f Department of Biomedical Engineering, 44 Cummington Street, Boston University, Boston, MA, USA