| 血管内皮生长因子与糖尿病视网膜病变的相关性研究 |
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| 引用本文： | 张昌莲,邹洪胜,李艳丽.血管内皮生长因子与糖尿病视网膜病变的相关性研究[J].中国医疗前沿,2010(7):58-58,79. |
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| 作者姓名： | 张昌莲 邹洪胜 李艳丽 |
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| 作者单位： | 山东省威海市荣成人民医院,264300 |
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| 摘 要： | 目的探讨血管内皮生长因子（VEGF）与糖尿病患者视网膜病变的相关性。方法应用ELISA检测糖尿病视网膜病变（DR）患者血清中VEGF水平。结果各组糖尿病患者VEGF水平均高于对照组（p〈0.05）,DR患者VEGF水平在患者视网膜病变的初期显著升高（p〈0.01）,到增殖期VEGF水平明显下降（p〈0.05）。结论VEGF水平与新生血管活动呈正相关。检测DR患者VEGF水平有助于了解该病患者的病情发展。
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| 关 键 词： | VEGF 糖尿病视网膜病变 糖尿病 |
The association between VEGF and diabetes retinpathy |
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| ZHANG Chang-lian,ZOU Hong-sheng,Li Yan-li.The association between VEGF and diabetes retinpathy[J].China Healthcare Innovation,2010(7):58-58,79. |
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| Authors: | ZHANG Chang-lian ZOU Hong-sheng Li Yan-li |
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| Institution: | ,(Department of Clinical Laboratory,Rongcheng People＇s hospital,Rongcheng 264300,China) |
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| Abstract: | Objective To investigate the correlation between vascular endothelial growth factor（VEGF） and microangiopathy in diabetes mellitus.Methods The levels of serum VEGF were detected by ELISA in diabetes retinopathy（DR）.Results VEGF increased significantly in the initial stage of retinopathy in DR（p〈 0.05）.Conclusion While in the proliferative stage VEGF showed no change.Positive correlation existed between VEGF and neovascular activity.The results showed that detection of VEGF in DR was useful in the evaluation of development of DR. |
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| Keywords: | VEGF Diabetes Mellitus Diabetes retinopathy |
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