| 缺铁性贫血合并反复呼吸道感染患儿细胞免疫功能观察 |
| |
| 引用本文： | 刘文彬 蒋安民. 缺铁性贫血合并反复呼吸道感染患儿细胞免疫功能观察[J]. 中华血液学杂志, 1997, 18(11): 566-567 |
| |
| 作者姓名： | 刘文彬 蒋安民 |
| |
| 作者单位： | 解放军第六十医院儿科 |
| |
| 摘 要： | 目的：测定６３例缺铁性贫血（ＩＤＡ）合并反复呼吸道感染（ＲＲＩ）患儿外周血白细胞介素２（ＩＬ－２）活性、血清可溶性白细胞介素２受体（ｓＩＬ－２Ｒ）水平和Ｔ淋巴细胞亚群，并分析它们之间的相关性。方法：ＩＬ－２活性和ｓＩＬ－２Ｒ水平测定分别采用ＭＴＴ法和双抗体夹心法，Ｔ淋巴细胞亚群测定采用ＡＰＡＡＰ法。结果：ＩＬ－２活性，ＣＤ３＋、ＣＤ４＋细胞百分率和ＣＤ４＋／ＣＤ８＋细胞比值均显著低于对照组（Ｐ均＜０．０１），而ｓＩＬ－２Ｒ水平显著高于对照组（Ｐ＜０．０１），ＣＤ８＋细胞百分率无明显变化。结论：ＩＤＡ合并ＲＲＩ患儿细胞免疫功能低下且紊乱。
|
| 关 键 词： | 贫血.低色素性 呼吸道感染 白细胞介素2 受体.白细胞介素2 T-淋巴细胞亚群 |
Cellular immunity in childhood iron deficiency anemia with recurrent respiratory infections |
| |
| W Liu,A Jiang,C Guo. Cellular immunity in childhood iron deficiency anemia with recurrent respiratory infections[J]. Chinese Journal of Hematology, 1997, 18(11): 566-567 |
| |
| Authors: | W Liu A Jiang C Guo |
| |
| Affiliation: | PLA No. 60 Hospital, Yunnan Dali 671003. |
| |
| Abstract: | OBJECTIVE: To examine interleukin-2 (IL-2) activity,serum soluble IL-2 receptor (sIL-2R) level and T lymphocyte subsets in peripheral blood from 63 childhood iron deficiency anemia (IDA) patients with recurrent respiratory infections(RRI). METHODS: IL-2 activity, sIL-2R level and T lymphocyte subsets were assayed by MTT, ELISA and APAAP, respectively. RESULTS: IL-2 activity, percentages of CD3+ and CD4+ cells as well as the ratio of CD4+/ CD8+ cells in the patients were significantly lower ( P < 0.01),while sIL-2R levels were higher than that in normal controls (P < 0.01). No significant change was found in the percentage of CD8+ cells. CONCLUSION: Cellular immunity was impaired in childhood IDA with RRI. |
| |
| Keywords: | |
| 本文献已被 CNKI 维普 等数据库收录！ |
