食管癌患者检测幽门螺杆菌的临床意义 |
| |
引用本文: | 陈健,施民新,刘继斌.食管癌患者检测幽门螺杆菌的临床意义[J].陕西肿瘤医学,2009,17(10):1865-1866. |
| |
作者姓名: | 陈健 施民新 刘继斌 |
| |
作者单位: | 江苏省南通大学附属肿瘤医院,江苏南通226361 |
| |
摘 要: | 目的:探讨幽门螺杆菌(Hp)检测在食管癌术后复发中的价值。方法:2002年-2004年食管鳞癌患者80例(胸上段癌4例,胸中段癌56例,胸下段癌20例),作为实验组。正常人和胃十二指肠良性疾病患者80例作为对照组。其中实验组再分为抗癌+抗Hp治疗及单纯抗癌治疗组各40例。快速尿素酶试验及Warthin—Strarry银染色检测Hp,ELISA法检测血中抗HpIgG抗体。结果:对照组食管Hp的感染率为21.25%(17/80),实验组为92.5%(74/80),两组差异显著(P〈0.05)。对照组血清抗HpIgG抗体阳性率为10%(8/80),实验组为55%(44/80),差异有显著性(P〈0.05)。食管癌切除术后抗癌+抗Hp治疗组Hp的感染率为12.5%(5/40),单纯抗癌治疗组达90%(36/40)(P〈0.05),随访3年抗癌+抗Hp治疗组食管癌复发率为22.5%(9/40),单纯抗癌治疗组食管癌复发率为42.5%(17/40)(P〈0.05)。结论:幽门螺杆菌感染与食管癌复关系密切。
|
关 键 词: | 幽门螺杆菌 食管癌 复发转移 |
Relationship between helicobacter pylori infection and esophageal cancer with metastasis |
| |
Institution: | CHEN Jian, SHI Min - xin, LIU Ji - bin( Nantong Tumor Hospital ,Nantong 226361, China.) |
| |
Abstract: | Objective: To study the relationship between helicobacter pylori infection and esophageal cancer. Methods: Eighty cases with esophageal cancer were studied and 80 healthy subjects as control. HP of esophageal tissue was detected by both Warthin - starry method and RUT. Anti - HplgG was measured by ELISA. Results : Hp infection rate was 21.25% in the control group,while it was as high as 92.5% in cancer pat ients(P 〈0.05). The positive rate of HplgG was 10% ,but it was as high as 55% in the study group(P 〈0.05). The metastasis rate in anti - Hp group was significantly lower than that in without anti - Hp group ( P 〈 0. 05 ). Conclusion: Hp infection of esophagus is associated with the incidence and development of esophageal cancer. |
| |
Keywords: | helicobacter pylori (Hp) esophageal cancer metastasis |
本文献已被 维普 等数据库收录! |
|