| 腺苷酸激活蛋白激酶在脂肪组织中的作用 |
| |
| 引用本文： | 秦媛媛,凌文华.腺苷酸激活蛋白激酶在脂肪组织中的作用[J].国外医学：内科学分册,2009,36(10):601-605. |
| |
| 作者姓名： | 秦媛媛 凌文华 |
| |
| 作者单位： | 中山大学公共卫生学院,广东广州510080 |
| |
| 摘 要： | 腺苷酸激活蛋白激酶（AMPK）是细胞和机体能量代谢的主要调节器。组织缺氧、低血糖、禁食和运动可以激活脂肪细胞中的AMPK。AMPK活化后能通过磷酸化下游信号分子，刺激能量生成途径（葡萄糖转运，脂肪酸氧化）关闭能量消耗的途径（脂肪、蛋白质、糖类的生成）。现在已经明确脂肪组织不仅是能量储存的场所，也在能量平衡以及其它很多过程中发挥作用。研究AMPK与脂肪组织的关系，将为AMPK作为防治肥胖的新靶点提供可靠的理论基础和应用依据。
|
| 关 键 词： | 腺苷酸激活蛋白激酶(AMPK) 脂肪组织 脂肪细胞 |
The function of adenine monophosphate activated protein kinase in adipose tissue |
| |
| QIN Yuan-yuan,LING Wen-hua.Faculty of Nutrition.The function of adenine monophosphate activated protein kinase in adipose tissue[J].Foreign Medical Sciences(Section of Internal Medicine),2009,36(10):601-605. |
| |
| Authors: | QIN Yuan-yuan LING Wen-huaFaculty of Nutrition |
| |
| Institution: | QIN Yuan-yuan,LING Wen-hua.Faculty of Nutrition,Department of Public Health,Sun Yat-sen University,Guangzhou 510080,China |
| |
| Abstract: | The adenine monophosphate (AMP) activated protein kinase (AMPK) is a major regulator of energy metabolism at both the cell and whole body level.The activation of AMPK stimulates pathways which increase energy production (glucose transportation,fatty acid oxidation) and switches off pathways which consume energy (lipogenesis,protein synthesis,gluconeogenesis).And adipose tissue is not only the place for energy storing,but also plays a critical role in energy homeostasis and many other processes. |
| |
| Keywords: | Adenine monophosphate activated protein kinase Adipose tissue Adipocytes |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
