| 超声造影鉴别诊断甲状腺良恶性结节 |
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| 引用本文： | 周杨洋,汤顾航,王婧,邹建中. 超声造影鉴别诊断甲状腺良恶性结节[J]. 中国介入影像与治疗学, 2014, 11(4): 225-228 |
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| 作者姓名： | 周杨洋 汤顾航 王婧 邹建中 |
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| 作者单位： | 重庆医科大学生物医学工程学院 省部共建超声医学工程国家重点实验室 超声医学工程重庆市市级重点实验室, 重庆 400016;重庆医科大学生物医学工程学院 省部共建超声医学工程国家重点实验室 超声医学工程重庆市市级重点实验室, 重庆 400016;重庆医科大学附属第一医院超声科, 重庆 400016;重庆医科大学生物医学工程学院 省部共建超声医学工程国家重点实验室 超声医学工程重庆市市级重点实验室, 重庆 400016 |
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| 基金项目： | 国家重点基础研究发展计划（973计划）项目（2011CB707900）、国家“十二五”科技支撑计划课题项目（2011BAI14B01）。 |
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| 摘 要： | 目的探讨CEUS鉴别诊断甲状腺良恶性结节的价值。方法回顾性分析62例患者67个甲状腺结节的CEUS表现。结果甲状腺恶性结节CEUS多表现为不均匀增强、边界不清,甲状腺良性结节多表现为周边环状强化。根据不均匀强化诊断恶性结节的敏感度为86.84%,特异度为44.83%,阳性预测值为67.35%,阴性预测值为72.22%;边界不清诊断恶性结节的敏感度81.58%,特异度65.52%,阳性预测值75.61%,阴性预测值73.08%;环状强化诊断良性结节的敏感度41.38%,特异度97.37%,阳性预测值92.31%,阴性预测值68.52%。结论 CEUS对鉴别诊断甲状腺良恶性结节具有一定价值。
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| 关 键 词： | 甲状腺结节 超声检查 造影剂 |
| 收稿时间： | 2013-07-24 |
| 修稿时间： | 2013-11-07 |
CEUS in differential diagnosis of benign and malignant thyroid nodules |
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| ZHOU Yang-yang,TANG Gu-hang,WANG Jing and ZOU Jian-zhong. CEUS in differential diagnosis of benign and malignant thyroid nodules[J]. Chinese Journal of Interventional Imaging and Therapy, 2014, 11(4): 225-228 |
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| Authors: | ZHOU Yang-yang TANG Gu-hang WANG Jing ZOU Jian-zhong |
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| Affiliation: | State Key Laboratory of Ultrasound Engineering in Medicine Co-founded by Chongqing and the Ministry of Science and Technology, Chongqing Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing 400016, China;State Key Laboratory of Ultrasound Engineering in Medicine Co-founded by Chongqing and the Ministry of Science and Technology, Chongqing Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing 400016, China;Department of ultrasound, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China;State Key Laboratory of Ultrasound Engineering in Medicine Co-founded by Chongqing and the Ministry of Science and Technology, Chongqing Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing 400016, China |
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| Abstract: | Objective To investigate the value of CEUS in differential diagnosis of benign and malignant thyroid nodules. Methods CEUS characteristics of 67 thyroid nodules in 62 patients were retrospectively analyzed. Results Thyroid carcinomas showed heterogeneous enhancement and irregular margin more often than benign nodules, while ring enhancement often occurred in benign ones. Heterogeneous enhancement and irregular margin often indicated carcinoma, and the sensitivity, specificity, positive predictive value and negative predictive value were 86.84% and 81.58%, 44.83% and 65.52%, 67.35% and 75.61%, 72.22% and 73.08%, respectively. Ring enhancement often indicated benign nodule, and the sensitivity, specificity positive, predictive value and negative predictive value was 41.38%, 97.37%, 92.31% and 68.52%, respectively. Conclusion CEUS is valuable in differentiating benign thyroid nodules from malignant ones. |
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| Keywords: | Thyroid nodule Ultrasonography Contrast media |
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