首页 | 本学科首页   官方微博 | 高级检索  
检索        


Non-linear short-term effects of airborne pollen levels with allergenic capacity on asthma emergency room admissions in Madrid, Spain
Authors:A Tobías †  I Galán‡  J R Banegas†
Institution:Department of Statistics and Econometrics, Universidad Carlos III de Madrid, Getafe, Spain. atobias@est-econ.uc3m.es
Abstract:BACKGROUND: Several time-series studies have shown positive associations between pollen levels and asthma morbidity. However, few studies have included air pollution as a potential confounder when examining this relationship, and they have only done so on a linear basis. OBJECTIVE: To investigate the potential non-linear short-term effects of the types of pollen with allergenic capacity across the whole range of exposure on the daily number of asthma-related hospital emergencies in Madrid for the period 1995-1998. METHODS: Data were collected on the daily number of asthma emergency room admissions and daily average levels of major types of pollen with allergenic capacity: Olea, Plantago, Poaceae and Urticaceae. We used Poisson regression with generalized additive models, controlling for trend and seasonality, meteorological variables, acute respiratory infections and air pollutants. To study the non-linear effect of pollen levels on asthma emergency room admissions, pollens were categorized into five groups defined on the basis of their respective distributions. RESULTS: The strongest associations were registered in respect of a lag of 1 day for Urticaceae, a lag of 2 days for Plantago, and a day lag of 3 days for Poaceae. Adjustment for the different types of pollen failed to result in major changes. Non-linearities were evident for pollen levels. The greatest increase in risk vs. the reference category (minimum value - 50th percentile) was observed for the categories between the 95th and 99th percentiles, with increases of 32.0% for Plantago, 32.2% for Poaceae and 24.6% for Urticaceae, and between the 99th percentile and the maximum value, with increases of 31.3%, 78.7% and 49.8%, respectively. Olea was not related with asthma emergency room admissions. CONCLUSIONS: Pollens with allergenic capacity in Madrid are positively associated with asthma-related hospital emergencies. These associations remain stable when simultaneous adjustment is made for the four types of pollen and for air pollutants and meteorological variables. In terms of non-linear effects, Poaceae register the strongest association with asthma emergency room admissions.
Keywords:air pollution  asthma emergency room admissions  non-linear effects  pollen  time-series regression
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号