| 急慢性肝炎患者红细胞免疫粘附功能变化 |
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| 引用本文： | 孙自勤,王要军,权启镇,肖瑞明,郭峰.急慢性肝炎患者红细胞免疫粘附功能变化[J].世界胃肠病学杂志(英文版),1996,2(1):20-21. |
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| 作者姓名： | 孙自勤 王要军 权启镇 肖瑞明 郭峰 |
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| 作者单位： | 济南军区总医院消化科，济南军区总医院消化科，济南军区总医院消化科，第二军医大学长海医院，第二军医大学长海医院 山东省济南市 250031 中国，山东省济南市 250031 中国，山东省济南市 250031 中国，上海市 200433 中国，上海市 200433 中国 |
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| 摘 要： | 目的探讨各型肝炎时红细胞免疫粘附功能的变化。方法用红细胞 C_3b 受体花环及免疫复合物花环法测定了42例急慢性肝炎患者活动期及恢复期的红细胞免疫粘附功能.同时测定了血浆免疫复合物水平变化。结果 B 型肝炎活动期红细胞 C_3b 受体花环形成率明显下降,分别为:急性肝炎13.54%±5.23%,急性重症肝炎7.61%±4.12%,慢性肝炎13.96%±5.01%,均低于正常(18.12%±3.91%)。恢复期则逐渐回升。红细胞免疫复合物花环及血浆免疫复合物均高于正常。结论急慢性肝炎时红细胞免疫粘附功能下降,其下降幅度与病情程度呈正比。
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| 关 键 词： | 肝炎 病毒性 人/免疫学 红细胞/免疫学 抗原-抗体复合物/血液 |
| 收稿时间： | October 30, 1995 |
Alterations of red blood cell immunoadherence function in hepatitis B patients |
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| Zi-Qin Sun,Yao-Jun Wang,Qi-Zhen Quan,Rui-Ming Xiao,Feng Guo.Alterations of red blood cell immunoadherence function in hepatitis B patients[J].World Journal of Gastroenterology,1996,2(1):20-21. |
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| Authors: | Zi-Qin Sun Yao-Jun Wang Qi-Zhen Quan Rui-Ming Xiao Feng Guo |
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| Institution: | Zi-Qin Sun, Yao-Jun Wang, Qi-Zhen Quan, Department of Gastroenterology, general Hospital of Chinese PLA Jinan Commanding Area, Jinan 250031, Shandong Province, ChinaRui-Ming Xiao, Professor of Infectious Diseases, Changhai Hospital, Second Military Medical University, Shanghai 200433, ChinaFeng Guo, Professor of Immunology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China |
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| Abstract: | AIM: To investigate the alterations of red blood cell (RBC) immunoadherence function in patients with hepatitis B.
METHODS: RBCC3bRR, RBCICRR and serum CIC levels were measured in 42 patients with acute and chronic hepatitis B at active and convalescence stages.
RESULTS: RBCC3bRRs at the active/acute stage of hepatitis were decreased, with 13.54% ± 5.23% in acute hepatitis, 7.61% ± 4.12% in acute fulminant hepatitis, and 16.18% ± 6.10% in chronic hepatitis, all of which were lower than the value in normal persons (18.12% ± 3.91%). At the quiescent/recovery stage of hepatitis, the RBCC3bRRs were increased significantly. The changes of RBCICRR and serum CIC level were contrary to those of RBCC3bRR.
CONCLUSION: RBC immunoadherence function is decreased in acute and chronic hepatitis, and the decrease is in direct proportion to severity of the diseases. |
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| Keywords: | hepatitis viral human/immunology erythrocytosis/immunology autigen-antibody complex/blood |
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