| 幽门螺杆菌疫苗研究的现状和展望 |
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| 引用本文： | 陈旻湖,焦志勇. 幽门螺杆菌疫苗研究的现状和展望[J]. 临床内科杂志, 2003, 20(2): 63-65 |
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| 作者姓名： | 陈旻湖 焦志勇 |
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| 作者单位： | 中山大学附属第一医院消化内科,广州,510080 |
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| 摘 要： | 幽门螺杆菌感染与慢性胃炎、消化性溃疡、胃癌及胃粘膜相关性淋巴瘤有关。疫苗是防治幽门螺杆菌感染切实可行的方法。近年来新的防治和根除幽门螺杆菌感染的疫苗正在开发并取得了很大的进展。本文对新近研制的蛋白组分疫苗、活菌疫苗、DNA疫苗、缓释微球疫苗及表位疫苗等幽门螺杆菌疫苗的进展作一综述。
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| 关 键 词： | 幽门螺杆菌感染 疫苗 现状 展望 蛋白组分疫苗 活菌疫苗 DNA疫苗 缓释微球疫苗 表位疫苗 |
| 文章编号： | 1001-9057(2003)02-0063-03 |
Recent developments in Helicobacter pylori vaccination |
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| CHEN Minhu,JIAO Zhiyong. Recent developments in Helicobacter pylori vaccination[J]. Journal of Clinical Internal Medicine, 2003, 20(2): 63-65 |
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| Authors: | CHEN Minhu JIAO Zhiyong |
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| Affiliation: | CHEN Minhu,JIAO Zhiyong.Department of Gastroenterology,The First Affiliated Hospital,Sun Yat-sen University,Guangzhou 510080,China |
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| Abstract: | Helicobacter pylori infection is associated with chronic gastritis,peptic ulcer disease,gastric adenocarcinoma and gastric mucosa-associated lymphoid tissue lymphoma. Vaccination is a feasible method against Hp infection. Recently new vaccination strategies for the prevention and eradication of Hp infections are being explored. Great progresses were obtained in this field. This review discussed newly developed vaccines against Hp infection such as protein component vaccine, gene-engineering bacterial vaccine,DNA vaccine, controlled release microparticles vaccine, epitope vaccine. |
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| Keywords: | Helicobacter pylori Vaccine Helicobacter pylori infection |
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