Regulation of TRP channels by PIP2 |
| |
| Authors: | Tibor Rohacs |
| |
| Institution: | (1) Department of Pharmacology and Physiology, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark, NJ 07103, USA |
| |
| Abstract: | Transient receptor potential (TRP) channels are regulated by a wide variety of physical and chemical factors. Recently, several
members of the TRP channel family were reported to be regulated by phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2, PIP2). This review will summarize the current knowledge on PIP2 regulation of TRP channels and discuss the possibility that PIP2 is a common regulator of mammalian TRP channels. |
| |
| Keywords: | TRP channels PIP2 PtdIns(4 5)P2 Phosphoinositides Ion channels TRPM channels TRPV channels TRPC channels |
| 本文献已被 PubMed SpringerLink 等数据库收录！ |
|
