| Effect of Shengmai Injection (生脉注射液) on cardiac function and inflammatory reaction in patients with acute coronary syndrome |
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| 引用本文： | 张亚臣,陈瑞明,吕宝经,荣烨之.Effect of Shengmai Injection (生脉注射液) on cardiac function and inflammatory reaction in patients with acute coronary syndrome[J].Chinese Journal of Integrated Traditional and Western Medicine,2008,14(2):107-110. |
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| 作者姓名： | 张亚臣 陈瑞明 吕宝经 荣烨之 |
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| 作者单位： | [1]Department of Internal Cardiology, Xinhua Hospital Affiliated to Shanghai Jiaotong Medical University School of Medicine, Shanghai （200092）, China [2]Department of Laboratory, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai （200025）, China |
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| 摘 要： | Objective： To confirm the effect of Shengmai Injection （生脉注射液, SMI） in improving cardiac function in patients with acute coronary syndrome （ACS） and to explore its influence on inflammatory reaction in patients. Methods： Ninety ACS patients were randomized into two groups, the control group treated with conventional therapy and the SMI group treated with SMI. The patients＇ cardiac function was noted and the content of high sensitive C-reactive protein （hs-CRP） in venous blood was measured before treatment and 1 week and 3 weeks after treatment, so as to observe and compare their changes between the two groups. Results： The cardiac output, stroke volume and ejection fraction in the SMI group after 3 weeks of treatment were all higher than those in the control group （P〈0.05）. The serum content of hs-CRP was reduced in both groups （P〈0.05）, but the reduction in the SMI group was more significant than that in the control group （P〈0.05）. Conclusion： SMI could improve the cardiac function and further inhibit the inflammatory reaction in patients with ACS.
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| 关 键 词： | 急性冠状动脉综合症 生脉注射液 C-反应蛋白 强心功能 |
| 收稿时间： | 26 January 2009 |
Effect of Shengmai Injection on cardiac function and inflammatory reaction in patients with acute coronary syndrome |
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| Authors: | Ya-chen Zhang Rui-ming Chen Bao-jing Lu and Ye-zhi Rong |
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| Institution: | Department of Internal Cardiology, Xinhua Hospital affiliated to Shanghai Jiaotong Medical University School of Medicine, Shanghai, China. zhangyachen65@yahoo.com.cn |
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| Abstract: | OBJECTIVE: To confirm the effect of Shengmai Injection (, SMI) in improving cardiac function in patients with acute coronary syndrome (ACS) and to explore its influence on inflammatory reaction in patients. METHODS: Ninety ACS patients were randomized into two groups, the control group treated with conventional therapy and the SMI group treated with SMI. The patients' cardiac function was noted and the content of high sensitive C-reactive protein (hs-CRP) in venous blood was measured before treatment and 1 week and 3 weeks after treatment, so as to observe and compare their changes between the two groups. RESULTS: The cardiac output, stroke volume and ejection fraction in the SMI group after 3 weeks of treatment were all higher than those in the control group (P<0.05). The serum content of hs-CRP was reduced in both groups (P<0.05), but the reduction in the SMI group was more significant than that in the control group (P<0.05). CONCLUSION: SMI could improve the cardiac function and further inhibit the inflammatory reaction in patients with ACS. |
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| Keywords: | Shengmai Injection acute coronary syndrome C-reactive protein inflammatory reaction cardiac function |
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