| 从软骨的病理改变研究大骨节病的病因 |
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| 引用本文： | 任宏造 彭麟. 从软骨的病理改变研究大骨节病的病因[J]. 地方病通报, 1991, 6(2): 18-20 |
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| 作者姓名： | 任宏造 彭麟 |
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| 作者单位： | 辽宁省基础医学研究所病理室电镜室 沈阳市(任宏造)，辽宁省基础医学研究所病理室电镜室 沈阳市(彭麟) |
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| 摘 要： | 在研究大骨节病的病因时,作者认为主要应考虑(1)病因因素必须和流行病学调查相符合,(2)以病因因素作动物实验时,应能复制出类似人大骨节病病理改变的模型。 大骨节病软骨的病理改变为软骨细胞的坏死,因此作详细的光镜及电镜对比观察,判断哪一种因素引起的软骨细胞坏死,最近似人大骨节病的病理改变,这对于理解大骨节病的病因、发病机制及进行防治,都是有用的。
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| 关 键 词： | 软骨 病理效应 大骨节病 病因 |
An Etiological Study of Kaschin-Beck Disease by Observing the Patho-logical Changes of the Chondrocyte |
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| Ren Hong-zao,Peng Ling. An Etiological Study of Kaschin-Beck Disease by Observing the Patho-logical Changes of the Chondrocyte[J]. Endemic Diseases Bulletin, 1991, 6(2): 18-20 |
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| Authors: | Ren Hong-zao Peng Ling |
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| Abstract: | The cause of Kaschin-Beck disease is not fully understood. Early pathological Changes include necroses of chondrocytes in joints and epiphyseal plates with low selenium levels in children suffering from the disease. However, hyposelenium didn't cause necrosis of chondrocytes in experimental animals, suggesting that hyposelenium might not the cause of Kaschin-Beck disease, but only a conditional factor. The authors, therefore, considered that the pathogeny of Kaschin-Beck disease may be the effect of the intoxication of a kind of poisonal substance based on hyposelenium. |
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| Keywords: | Kaschin-Beck disease Ultrastructure Pathology |
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