胃癌淋巴结转移规律的临床研究

目的：探讨胃癌淋巴结转移规律和胃癌根治术的淋巴结清扫范围。方法：将采集不同部位的淋巴结，依据国际TNM分期标准和组站分类法，全部数据进行统计学处理。结果：本组胃癌淋巴结转移率67．3％，早期和进展期胃癌转移率分别为14．3％和79．8％。肿瘤浸润深度T1者，淋巴结转移主要局限于N1，T2者淋巴结转移N3者5．4％，T3者淋巴结转移N3的9．5％。结论：胃癌淋巴结转移通常从原发病灶开始，通过淋巴网沿着淋巴管由近及远地向外扩散，肿瘤的大小或浸润深度不同，淋巴结转移的差异性有显著意义（P＜0．01）。

CLINICAL STUDY ON THE RULES OF LYMPH NODE METASTASIS IN GASTRIC CANCER

Objective:To investigate the pattern of lymph node metastasis and the extent of lymph node dissection for gastric cancer.Methods:To collect lymph nodes in different parts and differentiate them according to international TNM standard,tissue methods and numerical statistics.Rusults:The total incidence of lymph nolde metastasis was 67.3%;node involvement was 14.3% and 79.8%,respectively for early gastric cancer and advanced gastric cancer.When the depth of invasion reached T 1,node involvement was mainly confined to N 1;5.4% of T 2 and 9.5% of T 3 patients had N 3 lymph node metastasis.Conclusion:Lymph node metastasis usually begins from the original focus,and diffuses from the near to the distance by lymph network and along lymphatic vessels.Depth of invasion, tumor size and histology affected lymph node metastasis significantly( P <0.01).