某部新兵自杀意念相关唾液生化分析

目的：探索早期筛查自杀高危人群无伤无害的生化指标。方法对某部2014年入伍第1个月的新兵727人，采用自杀意念自评量表（ SIOSS）进行自杀意念普查，以≥12分为划界分，有25人（实际27人，两人因故未参加）入自杀意念组，从无自杀意念的新兵中随机抽取25人作为对照组；分别在进入新兵训练1和3个月后采集唾液进行生化分析，同时采用SIOSS再次进行自杀意念测试。结果新兵训练1个月唾液生化分析显示，自杀意念组与无自杀意念对照组唾液钙、镁、淀粉酶（Amy）、唾液酸（SA）含量存在统计学差异（P＜0．05），但各项指标与SIOSS评分无显著直线相关（P＞0．05）；新兵训练3个月唾液生化分析显示，按首次自杀意念普查分成的自杀意念组与对照组唾液钙、镁、Amy、SA含量已无统计学差异（ P＞0．05）。结论新兵入伍第1个月，筛查出的自杀意念者唾液生化成分改变，可能与机体应激有关；采用唾液生化指标筛查自杀意念者缺乏生物学特异性。

A salivary biochemical analysis of recruits associated with suicidal ideation

Objective To investigate the harmless biochemical indicators for early screening of populations at high risk of suicide .Methods Seven hundred and twenty-seven new recruits were investigated according to self-rating idea of suicide scale (SIOSS) in the first month of recruitment in 2014.Twenty-five recruits (originally 27 recruits, but 2 recruits were absent from biochemical tests ) whose SIOSS scores were less than 12 were recognized as the suicidal ideation group. Another 25 recruits whose SIOSS scores were more than 12 were randomly selected as the control group .Saliva samples of the 50 recruits were collected for biochemical analysis after one month and three months of training , respectively .After three months of training , the SIOSS was also used for evaluation of suicidal ideation .Results After one-month training , the concentrations of Ca , Mg, amylase ( Amy ) and salivary acid ( SA ) in saliva were demonstrated to be statistically different between the suicidal ideation group and the control group ( P <0.05 ), but there was no significant linear correlation between these indicators and the SIOSS (P>0.05).After three-month training, the concentrations of Ca, Mg, Amy and SA in saliva between the two groups showed no significant difference (P>0.05).Conclusion After the first month training , changes in the biochemical compositions were found in the saliva of the screened recruits with suicidal ideation, which may be associated with the stress response of the body .The biochemical indicators in saliva lack specificity for suicidal ideation .