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Genetic analysis of isolation-induced aggression. II. Postnatal environmental influences in AB mice
Authors:Hans-Jürgen Hoffmann  Regine Schneider  Wim E. Crusio
Affiliation:(1) Institute of Brain Research, Brenneckestra"beta"e 6, D-O-3090 Magdeburg, Germany;(2) Génetique, Neurogénétique et Comportement, URA 1294 CNRS, UFR Biomédicale, Université René Descartes (Paris V), 45 rue des Saints-Pères, 75270 Paris Cedex 06, France
Abstract:Recently, we reported on two closely related inbred mouse strains, ABG and AB//Halle, that display extreme differences in isolation-induced intermale aggression. In the present article we investigated the influence of both maternal and social postnatal environmental influences. No effects were found of the postnatal maternal environment. Likewise, whether animals after weaning were housed together in same-strain or mixed-strain groups did not influence their subsequent aggressive behavior. We conclude that the aggressive behavior of ABG and AB//Halle is rather robust with regard to postnatal environmental modification and that the difference between the two strains is most likely due to only few genetic factors.
Keywords:Isolation-induced aggression  genotype  postnatal maternal effects  fostering  inbred strains of mice
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