Photodynamic therapy inhibits p-glycoprotein mediated multidrug resistance via JNK activation in human hepatocellular carcinoma using the photosensitizer pheophorbide a期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Photodynamic therapy inhibits p-glycoprotein mediated multidrug resistance via JNK activation in human hepatocellular carcinoma using the photosensitizer pheophorbide a

Authors:	Patrick Ming-Kuen Tang Dong-Mei Zhang Ngoc-Ha Bui Xuan Stephen Kwok-Wing Tsui Mary Miu-Yee Waye Siu-Kai Kong Wing-Ping Fong Kwok-Pui Fung

Affiliation:	(1) School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, PR China;(2) Department of Biochemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, PR China;(3) Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, PR China

Abstract:	Background Multidrug resistance (MDR) is frequently observed after prolonged treatment in human hepatoma with conventional anti-tumor drugs, and photodynamic therapy (PDT) is a recently suggested alternative to overcome MDR. The therapeutic potential of PDT was evaluated in a multidrug resistance (MDR) human hepatoma cell line R-HepG2 with photosensitizer pheophorbide a (Pa).

Keywords:
本文献已被 SpringerLink 等数据库收录！