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DNA hypermethylation contributes to incomplete synthesis of carbohydrate determinants in gastrointestinal cancer
Authors:Kawamura Yuki I  Toyota Minoru  Kawashima Rei  Hagiwara Teruki  Suzuki Hiromu  Imai Kohzoh  Shinomura Yasuhisa  Tokino Takashi  Kannagi Reiji  Dohi Taeko
Affiliation:Department of Gastroenterology, Research Institute, International Medical Center of Japan, Tokyo, Japan.
Abstract:
Keywords:5-aza-dC, 5-aza-2′-deoxycytidine   COBRA, combined bisulfite restriction analysis   DNMT, DNA methyltransferase   EBV, Epstein-Barr virus   FUT, fucosyltransferase   Gal, galactose   GalNAc, N-acetylgalactosamine   GALNT, N-acetylgalactosaminyltransferase   GAPDH, glyceraldehyde-3-phosphate dehydrogenase   GI, gastrointestinal   mAb, monoclonal antibody   HP, Helicobacter pylori   Sda-β1, 4GalNAcT, β1,4N-acetylgalactosaminyltransferase, which forms Sda carbohydrate determinants   ST, sialyltransferase   type II precursor, Galβ1,4GlcNAc-R
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