Synchronous,primary, diffuse,large b‐cell lymphomas involving the ethmoid sinus and epiglottis: A rare clinical entity |
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Authors: | Young‐Ho Yoon MD Won‐Young Park MD Young‐Jin Choi MD PhD Kyu‐Sup Cho MD PhD |
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Affiliation: | 1. Department of Otorhinolaryngology and Biomedical Research Institute, Busan, South Korea;2. Department of Pathology, Pusan National University School of Medicine, Busan, South Korea;3. Department of Hematology–Oncology, Pusan National University School of Medicine, Busan, South Korea |
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Abstract: | Non‐Hodgkin's lymphoma (NHL) affecting the ethmoid sinus and epiglottis is uncommon. Furthermore, synchronous NHLs involving the ethmoid sinus and epiglottis are extremely rare and have not been reported previously. This article reports synchronous, primary, diffuse, large B‐cell lymphoma (DLBCL) arising in the ethmoid sinus and epiglottis, which was successfully treated by immunochemotherapy. A careful examination of the head and neck is necessary to determine the existence of multiple synchronous primary tumors, because primary synchronous occurrence of DLBCL in the head and neck is unusual and can impact the prognosis adversely. Laryngoscope, 2013 |
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Keywords: | Lymphoma diffuse large B‐cell ethmoid sinus epiglottis neoplasms multiple primary R‐CHOP protocol |
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