MRI of ovarian masses |
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Authors: | Hebert Alberto Vargas MD Tristan Barrett MBBS BSc Evis Sala MD PhD |
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Affiliation: | 1. Department of Radiology, Memorial Sloan‐Kettering Cancer Center, New York, New York, USA;2. Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, United Kingdom |
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Abstract: | MRI provides exquisite views of the pelvic anatomy through its high spatial resolution and tissue contrast, and as such plays a key role in the work up of ovarian lesions, identifying features that distinguish benign and malignant lesions. In the case of primary tumors it enables local staging and detection of metastatic disease to help guide management options such as complex surgery or the consideration of neoadjuvant chemotherapy. Functional MRI techniques such as diffusion‐weighted MRI (DW‐MRI), dynamic contrast‐enhanced MRI (DCE‐MRI) and tumor‐selective molecular imaging are currently being evaluated as possible predictive and prognostic biomarkers in the context of ovarian malignancy, and may play a larger role in routine clinical practice in the future. Herein we provide an overview of the conventional and advanced MRI techniques used to characterize ovarian masses and of the role that MR plays in the staging, treatment selection and follow up of patients with ovarian cancer. J. Magn. Reson. Imaging 2013;37:265–281. © 2012 Wiley Periodicals, Inc. |
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Keywords: | ovarian cancer magnetic resonance imaging diffusion‐weighted MRI dynamic contrast‐enhanced MRI apparent diffusion coefficient |
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