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Improved parallel MR imaging using a coefficient penalized regularization for GRAPPA reconstruction
Authors:Wentao Liu  Xin Tang  Yajun Ma  Jia‐Hong Gao
Affiliation:1. Beijing City Key Lab for Medical Physics and Engineering, School of Physics, Peking University, , Beijing, China;2. MRI Research Center, Academy for Advanced Interdisciplinary Studies, Peking University, , Beijing, China;3. Brain Research Imaging Center and Department of Radiology, The University of Chicago, , Chicago, Illinois, USA
Abstract:A novel coefficient penalized regularization method for generalized autocalibrating partially parallel acquisitions (GRAPPA) reconstruction is developed for improving MR image quality. In this method, the fitting coefficients of the source data are weighted with different penalty factors, which are highly dependent upon the relative displacements from the source data to the target data in k‐space. The imaging data from both phantom testing and in vivo MRI experiments demonstrate that the coefficient penalized regularization method in GRAPPA reconstruction is able to reduce noise amplification to a greater degree. Therefore, the method enhances the quality of images significantly when compared to the previous least squares and Tikhonov regularization methods. Magn Reson Med 69:1109–1114, 2013. © 2012 Wiley Periodicals, Inc.
Keywords:parallel imaging  GRAPPA  image reconstruction  penalized regularization
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