| 吡喹酮水凝胶栓剂的含量测定 |
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| 引用本文： | 刘祖梅. 吡喹酮水凝胶栓剂的含量测定[J]. 现代医药卫生, 2005, 21(21): 2893-2893 |
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| 作者姓名： | 刘祖梅 |
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| 作者单位： | 荆门职业技术学院医学分院,湖北,荆门,448000 |
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| 摘 要： | 目的:制备吡喹酮水凝胶栓剂,并建立其含量测定方法。方法:用紫外分光光度法测定凝胶栓剂中吡喹酮的含量。结果:吡喹酮在0.2￣1.0mg/ml(r=0.9999)浓度范围内呈良好线性关系。平均加样回收率和相对标准偏差(RSD)为(102.44±0.69)%。结论:该处方设计合理,制备工艺可靠,质量稳定。
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| 关 键 词： | 吡喹酮 水凝胶栓剂 泊洛沙姆 |
| 文章编号： | 1009-5519(2005)21-2893-01 |
| 收稿时间： | 2005-08-01 |
| 修稿时间： | 2005-08-01 |
Preparation and determination of the content of thermo-reversible praziquantel liquid suppository |
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| LIU Zu-mei. Preparation and determination of the content of thermo-reversible praziquantel liquid suppository[J]. JOURNAL OF MODERN MEDICINE & HEALTH, 2005, 21(21): 2893-2893 |
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| Authors: | LIU Zu-mei |
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| Abstract: | Objective:To prepare the thermo-reversible praziquantel liquid suppository and establish the determination method of its content.Methods:The content of praziquantel in the thermo-reversible liquid suppository was measured by ultraviolet spectrophotometry.Results:The linear response range was 0.2~10 mg.ml-1(r=0.9999).The mean recovery was 102.44% with RSD=0.69%.Conclusion:The formulation is reasonable and the preparation is stable. |
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| Keywords: | Praziquantel Thermo-reversible liquid suppository Poloxamer |
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