| 纳豆激酶在大鼠机体内外对凝血功能的影响 |
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| 引用本文： | 邵玉英,聂凤环,马静洁.纳豆激酶在大鼠机体内外对凝血功能的影响[J].延边医学院学报,2010,33(1):10-12. |
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| 作者姓名： | 邵玉英 聂凤环 马静洁 |
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| 作者单位： | 邵玉英,聂凤环(延边大学草仙药业有限公司,吉林,龙井,133400);马静洁(延边大学药学院,吉林,延吉,133000) |
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| 摘 要： | 目的]探讨纳豆激酶对大鼠机体内外对凝血功能的影响.方法]通过对大鼠纤维蛋白原含量、凝血酶时间、添加小蓟的血浆凝固时间及优球蛋白溶解时间的测定,评价纳豆激酶对凝血功能的影响.结果]纳豆激酶可明显降低大鼠血浆纤维蛋白原含量,使添加小蓟的血浆不发生凝固,延长凝血酶时间,提高优球蛋白溶解活性.结论]纳豆激酶在大鼠体内外均具有较好的抗凝血作用.
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| 关 键 词： | 大豆食品 抗凝血酶类 凝血酶时间 血清球蛋白类 大鼠 |
Effects of the nattokinase for coagulation in vivo and in vitro in rats |
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| SHAO Yu-ying,NIE Feng-huan,MA Jing-jie.Effects of the nattokinase for coagulation in vivo and in vitro in rats[J].Journal of Medical Science Yanbian University,2010,33(1):10-12. |
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| Authors: | SHAO Yu-ying NIE Feng-huan MA Jing-jie |
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| Institution: | SHAO Yu-ying1,NIE Feng-huan1,MA Jing-jie2(1.Yanbian University Herbage Pharmaceuticial Company,Longjing 133400,Jilin,China,2.Yanbian University College of Pharmacy,Yanji 133000,China) |
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| Abstract: | OBJECTIVE To study the effects of the nattokinase for coagulation in vivo and in vitro in rats.METHODSThe effects of nattokinase for coagulation function were evaluated by measuring the fibrinogen,thrombin time,plasma coagulation time with adding the common thistle,and euglobulin lysis time in rats.RESULTSThe nattokinase reduced obviously the content of plasma fibrinogen,did not coagulate the plasma added with the common thistle,extended the thrombin time,and improved the euglobulin lytic activity in rats.C... |
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| Keywords: | soy foods antithrombins thrombin time serum globulins rats |
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