Abstract: | ABSTRACT: Hyperthermia was induced in rats twice at an interval of eight hours on both days 13 and 14 of gestation by partial immersion in a water-bath. Deep rectal temperature was raised to 42.5°C for five minutes. Body weights of newborn rats were reduced, but by three weeks of age compensatory post-natal growth had eliminated the defect. In both newborn and 21-day-old rats, brain weight was significantly reduced compared with controls of similar body weight. No other anomalies were found. |