Highlighting the versatility of the tracerlab synthesis modules. Part 1: fully automated production of [18F]labelled radiopharmaceuticals using a Tracerlab FXFN |
| |
| Authors: | Xia Shao Raphaël Hoareau Brian G Hockley Louis J M Tluczek Bradford D Henderson Henry C Padgett Peter J H Scott |
| |
| Institution: | 1. The University of Michigan School of Medicine, Ann Arbor, MI, USA;2. Cardinal Health, Los Angeles, CA, USA |
| |
| Abstract: | The field of radiochemistry is moving toward exclusive use of automated synthesis modules for production of clinical radiopharmaceutical doses. Such a move comes with many advantages, but also presents radiochemists with the challenge of re‐configuring synthesis modules for production of radiopharmaceuticals that require nonconventional radiochemistry while maintaining full automation. This review showcases the versatility of the Tracerlab FXFN synthesis module by presenting simple, fully automated methods for producing 18F]FLT, 18F]FAZA, 18F]MPPF, 18F]FEOBV, 18F]sodium fluoride, 18F]fluorocholine and 18F]SFB. Copyright © 2011 John Wiley & Sons, Ltd. |
| |
| Keywords: | positron emission tomography automated radiopharmaceutical synthesis fluorine‐18 radiochemistry |
|
|
