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Curcumin decreases cholangiocarcinogenesis in hamsters by suppressing inflammation‐mediated molecular events related to multistep carcinogenesis
Authors:Suksanti Prakobwong  Jarinya Khoontawad  Puangrat Yongvanit  Chawalit Pairojkul  Yusuke Hiraku  Paiboon Sithithaworn  Porntip Pinlaor  Bharat B. Aggarwal  Somchai Pinlaor
Affiliation:1. Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;2. Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;3. Department of Experimental Therapeutics, The University of Texas, M.D. Anderson Cancer Center, Houston, TX;4. Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;5. Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;6. Department of Environmental and Molecular Medicine, Mie University Graduate School of Medicine, Tsu, Mie, Japan;7. Centre for Research and Development in Medical Diagnostic Laboratory, Faculty of Associated Medical Science, Khon Kaen University, Khon Kaen, Thailand;8. Department of Experimental Therapeutics, The University of Texas, M.D. Anderson Cancer Center, Houston, TXTel.: 713‐794‐1817, Fax: 713‐794‐1613;9. Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandTel.: +66‐43‐348‐387, Fax: +66‐43‐202‐475
Abstract:
Keywords:Opisthorchis viverrini  cholangiocarcinoma  curcumin  DNA damage  apoptosis  cell proliferation  angiogenesis
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