丹参川芎嗪注射液治疗后循环缺血性眩晕的临床评价

目的 评价丹参川芎嗪治疗后循环缺血性眩晕的临床疗效。方法 选择2015年3月-2017年3月在安徽省中医院诊治的后循环缺血性眩晕患者80例，随机分为对照组和观察组，各40例。对照组患者口服甲磺酸倍他司汀，6 mg/次，3次/d；治疗组静脉滴注丹参川芎嗪注射液，10 mL/次加入0.9% NaCl 250 mL，1次/d，均用药2周；观察两组患者的疗效，并比较两组治疗前后临床症状等的改善程度；检测治疗前后血黏度、纤维蛋白原等实验室指标的变化。结果 治疗后，治疗组患者的总有效率92.5%，对照组的72.5%，两组比较差异有统计学意义（P<0.05）；血黏度和血纤维蛋白原较治疗前均有改善，且治疗组改善情况优于对照组，两组比较差异有统计学意义（P<0.05）。结论 丹参川芎嗪注射液治疗后循环缺血性眩晕的临床疗效较好，可以改善脑后循环血液供应，值得推广。

Clinical observation on Danshen Chuangxiongqin Injection in treatment of posterior circulation ischemia vertigo

Objective To observe the clinical effect of Danshen Chuangxiongqin Injection in treatment of posterior circulation ischemia vertigo. Methods Patients (80 cases) with posterior circulation ischemia vertigo attack in Anhui Hospital of Traditional Chinese from March 2015 to March 2017 were randomly divided into control and treatment groups, and each group had 40 cases. Patients in control group were treated by Betahistine mesylate, 6 mg/time (3 times/d) for 2 weeks. Patients in treatment group were iv administered with Danshen Chuangxiongqin Injection (10 mL/d) added into normal saline 250 mL, once daily for 2 weeks. After treatment, the efficacy was evaluated, and the levels of blood viscosity index, fibrinogen in two groups before and after treatment were compared. Results Total effective rate of observation group was 92.5% which was higher than the control group''s 72.5% with significant difference (P<0.05). After treatment, the laboratory indexes (levels of blood viscosity, fibrinogen, and so on) were decreased, the improvement degree of these indexes in treatment group were significantly better than those in control group, with significant difference between two groups (P<0.05). Conclusion Danshen Chuangxiongqin Injection has significant effect in treating posterior circulation ischemia vertigo and it is worthy of clinical application and promotion.