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The volumetric measurement of gastric emptying and gastric secretion by a radioisotope method
Authors:Ronald A Hinder MB  BCh  FRCS  FRCS  Bernard K P Horn PhD  Cedric G Bremner MCh  FRCS  FRCS
Institution:(1) Department of Surgery, University of the Witwatersrand, Medical School, Esselen Street, 2001 Johannesburg, Republic of South Africa;(2) Present address: the Artificial Intelligence Laboratory, Massachusetts Institute of Technology, 02139 Cambridge, Massachusetts
Abstract:Most methods of measurement of gastric emptying rely on the serial estimation of intragastric volume and do not separately account for the volume of fluid which has been added to the meal by gastric secretion, duodenal reflux, or swallowed saliva. The volume emptied is therefore underestimated. A method of measuring gastric emptying using 125I]RIHSA and the Volémetron is presented. The volume of fluid added to the meal is taken into consideration in this method, giving a more accurate reflection of gastric emptying. Using this method in the dog, emptying was found to be linear rather than exponential.Supported by South African Medical Research Council grant M14/71/51.
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