影响多发性肌炎和皮肌炎疗效的因素分析和对策

目的探讨影响多发性肌炎和皮肌炎疗效的因素和对策。方法通过对66例多发性肌炎和皮肌炎的临床资料和治疗方法进行分析。结果延误诊断、糖皮质激素用量不足和疗程不够、不及时加用免疫抑制剂、伴发肺间质病变或心肺功能差及恶性肿瘤是影响其疗效的因素。结论及早诊断,早期足量,尤其早期激素冲击并继之以长时间适当剂量糖皮质激素,及时加用其他免疫抑制剂、尽早发现肺间质疾病与排除恶性肿瘤,可提高疗效,改善预后。

Analysis and strategy of the factors that influence the efficacy of poly-myositis and dermatomyositis

Objective To study the analysis and strategy of the factors that influence the efficacy of polymyositis and dermatomyositis.Methods Through a retrospective analysis of 66 cases of polymyositis and dermatomyositis.Results Delay in diagnosis,glucocorticoid dosage and treatment are not enough,not timely with immunosuppressive agents,associated with interstitial lung disease,poor cardiopulmonary function,cancer are polymyositis and dermatomyositis efficacy factors.Conclusion Early diagnosis,early enough,especially early hormonal impact,followed by long-appropriate dose glucocorticoids,and in a timely manner with immunosuppressive agents,early detection of interstitial lung disease,early to rule out malignancy,these measures could improve the efficacy and improve the prognosis.