1102例乳腺癌巩固期证候分布规律临床研究

目的：探讨乳腺癌巩固期证候分布规律,并确立证型的主要四诊信息,为建立乳腺癌术后巩固期患者的辨证分型标准奠定基础。方法：对2009年6月至2012年6月于广东省中医院乳腺科门诊乳腺癌巩固期患者进行问卷调查,运用聚类分析法和＂频数归一化＂研究。结果：经专家确认,聚4类比较符合临床实际,分别是脾肾两虚证（占34.8%）、肾虚血瘀证（占27.9%）、肝肾阴虚证（占4.7%）、有病无证型（占32.5%）。结论：经过临床流行病学的统计分析方法确立了乳腺癌巩固期的辨证分型及证候指标,为该期患者的辨证论治提供理论依据。

Clinical Study on Syndrome Differentiation Patterns in 1102 Patients of Breast Cancer in Consolidate Period

Objective： To explore the syndrome differentiation patterns of breast cancer,indentify the main four diagnostic method information of the syndrome types,and establish foundation for setting up standards for syndrome differentiation types of consolidate period in patients with breast cancer after surgeries. Methods： Questionnaires were given to 1102 patients admitted to breast department of Guangdong province Hospital of TCM from June 2009 to June 2012 who were on the consolidate period of breast cancer. Methods of category analysis and frequency normalization were used. Results： Four patterns were concluded to be clinically practical by the confirmation of experts,including spleen-kidney deficiency pattern（ 34. 8% ） ,kidney deficiency with blood stasis pattern（ 27. 9% ） ,deficiency of liver-kidney yin pattern （ 4. 7% ） and disease without syndrome pattern （ 32. 5% ） . Conclusion： epidemiology investigation and statistical analysis are used to establish the syndrome differentiation patterns and indexes for consolidate period of breast cancer,which provides theoretical evidence for treating patients in this phase.