银马抗病毒颗粒抗菌、抑制迟发性超敏免疫反应的实验研究

目的：研究银马抗病毒颗粒抑菌及对迟发性免疫反应的作用。方法：通过体外试管倍比稀释法及体内抗菌,观察银马抗病毒颗粒的抗菌作用;通过二硝基氟苯对小鼠致敏试验,观察银马抗病毒颗粒对小鼠的迟发性免疫反应的作用。结果：银马抗病毒颗粒药物浓度为0.125g·mL-1时,在体外对金黄色葡萄菌、乙型溶血性链球菌、甲型链球菌、绿脓杆菌及肺炎双球菌具有抑菌作用;银马抗病毒颗粒能降低致病菌对小鼠的死亡率;银马抗病毒颗粒具有抑制小鼠迟发性免疫反应的作用。结论：银马抗病毒颗粒具有体外、体内抑菌的作用,具有抑制迟发性超敏反应的作用。

Experimental Study on Antibacterial Effect and Inhibiting Delayed Type Hypersensitivity Function of Yinma Antiviral Granule

Objective： To study the antibacterial effect and function of inhibiting delayed type hypersensitivity of Yinma Antiviral Granule. Methods： The multiple proportion dilution method in vitro tube was used to observe the antibacterial effect of Yinma Antiviral Gran- ule. Sensitized experiment of initrofluorobenzene on mice was conducted to observe the function of Yinma Antiviral Granule on delayed type hypersensitivity. Results： Yinma Antiviral Granule in concentration of 0. 125 g？ mL-1 had antibacterial effect in vitro on staphylo-coccus bacteria,hemolytic streptococcus,group a streptococcus,pseudomonas aeruginosa and pneumococci; Yinma Antiviral Granule reduced mice mortality effected by pathogenic bacteria; Yinma Antiviral Granule inhibited delayed type hypersensitivity on mice. Conclusion： Yinma Antiviral Granule has internal and external antibacterial effect and it could inhibit delayed type hypersensitivity function.