| 妊娠糖尿病患者血浆视黄醇结合蛋白4水平与胰岛素抵抗的相关性分析 |
| |
| 引用本文： | 贾忠兰,卢新,刘敏,郭艳玲.妊娠糖尿病患者血浆视黄醇结合蛋白4水平与胰岛素抵抗的相关性分析[J].上海医学检验杂志,2009(8). |
| |
| 作者姓名： | 贾忠兰 卢新 刘敏 郭艳玲 |
| |
| 作者单位： | 北京海淀区妇幼保健院检验科; |
| |
| 摘 要： | 目的检测妊娠糖尿病患者血浆视黄醇结合蛋白4(RBP4)的水平,探讨其与胰岛素抵抗的关系。方法用酶联免疫分析法测定37例正常妊娠妇女及40例妊娠糖尿病患者血浆RBP4水平,同时测定空腹血糖、血脂及胰岛素水平,并计算稳态模型胰岛素抵抗指数(HOMA-IR)。结果妊娠糖尿病患者血浆RBP4水平(28.52±12.45)μg/mL]虽低于正常妊娠妇女组(31.47±14.28)μg/mL],但差异无统计学意义(P>0.05)。RBP4与HOMA-IR、空腹血糖呈正相关相关系数(r)分别为0.34、0.37,P<0.05]。结论妊娠糖尿病患者空腹RBP4水平有下降的趋势但没有显著变化。RBP4水平与空腹血糖、HOMA-IR有关。
|
| 关 键 词： | 视黄醇结合蛋白4 妊娠 糖尿病 胰岛素抵抗 |
Relationship between retinol-binding protein-4 and insulin resistance in gestational diabetes mellitus |
| |
| JIA Zhonglan,LU Xin,LIU Min,GUO Yanling..Relationship between retinol-binding protein-4 and insulin resistance in gestational diabetes mellitus[J].Shanghai Journal of Medical Laboratory Sciences,2009(8). |
| |
| Authors: | JIA Zhonglan LU Xin LIU Min GUO Yanling |
| |
| Institution: | Department of Clinical Laboratory;Haidian Maternal & Child Health Hospital;Beijing 100080;China |
| |
| Abstract: | Objective To investigate the correlation between retinol-binding protein-4(RBP4) level and insulin resistance in gestational diabetes mellitus(GDM). Methods The levels of plasma RBP4 in 40 pregnant women with GDM and 37 normal pregnant women were determined by enzyme-linked immunosorbent assay(ELISA).The levels of fasting blood glucose,insulin,total cholesterol and triglyceride were determined,and homeostasis model assessment insulin resistance index(HOMA-IR) was calculated.Results The plasma RBP4 level had... |
| |
| Keywords: | Retinol-binding protein-4 Gestation Diabetes mellitus Insulin resistance |
| 本文献已被 CNKI 等数据库收录！ |
