| 藏药八味沉香散95％醇提液对垂体后叶素致心肌缺血损伤大鼠的血流动力学的影响 |
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| 引用本文： | 沈国平,寇毅英,李永芳.藏药八味沉香散95％醇提液对垂体后叶素致心肌缺血损伤大鼠的血流动力学的影响[J].青海医学院学报,2011,32(4):231-234. |
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| 作者姓名： | 沈国平 寇毅英 李永芳 |
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| 作者单位： | 青海大学医学院 |
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| 基金项目： | 青海省科技厅资助(项目编号:2005-J-801) |
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| 摘 要： | 目的 研究藏药八味沉香散95％醇提液对垂体后叶素(PIT)诱发大鼠急性心肌缺血后血流动力学的影响.方法 采用大鼠舌下静脉注射垂体后叶素复制大鼠急性心肌缺血模型,观察八味沉香散95％醇提液对大鼠注射垂体后叶素后不同时间血流动力学的变化.结果 八味沉香散95％醇提大、小剂量组使心肌缺血降低的LVSP和±dp/dtmax升高...
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| 关 键 词： | 八味沉香散 心肌缺血 垂体后叶素 血流动力学 |
THE HEMODYNAMIC EFFECT OF 95% ALCOHOL-EXTRACT FROM TIBETAN HERB BAWEI CHENXIANG POWDER ON MYOCARDIAL ISCHEMIA INDUCED BY PITUITRIN IN RATS |
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| Shen Guoping,Kou Yiying,Li Yongfang.THE HEMODYNAMIC EFFECT OF 95% ALCOHOL-EXTRACT FROM TIBETAN HERB BAWEI CHENXIANG POWDER ON MYOCARDIAL ISCHEMIA INDUCED BY PITUITRIN IN RATS[J].Journal of Qinghai Medical College,2011,32(4):231-234. |
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| Authors: | Shen Guoping Kou Yiying Li Yongfang |
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| Institution: | Shen Guoping,Kou Yiying,Li Yongfang(Qinghai University Medical College) |
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| Abstract: | Objective To study the hemodynamic effect of 95% alcohol -extract from Tibetan herb Bawei Chenxiang powder in rats with myocardial injury induced by pituitrin. Methods Myocardial ischemia model on rats was established by pituitrin injected intravenously. After injecting pituitrin, hemodynamic such as the LVSP, ±dp/dtmax and LVEDP were measured. Results Compared with the Pit model group, the baweichanxiang pretreated group shown an increased level of LVSP and ＋ dp/dtmax, but the level of LVEDP was decreased （P 〈 0.05 or P 〈 0. 01 ）. there were no significant difference in blood pressure between two groups（ P 〉 0. 05 ）. Conclusion These results suggested that the 95 % alcohol - extract from Tibetan herb Bawei Chenxiang is able to protect cardiac systolic and diastolic function during acute myocardial ischemia caused by pituitrin. |
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| Keywords: | Bawei chenxiang powder Pituitrin Myocardial ischemia |
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