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小儿病毒性脑膜炎病原学调查
引用本文:陈伟明,卢远达,刘集鸿. 小儿病毒性脑膜炎病原学调查[J]. 热带医学杂志, 2006, 6(2): 214-215
作者姓名:陈伟明  卢远达  刘集鸿
作者单位:广东省惠州市中心人民医院,惠州,516001;广东省惠州市中心人民医院,惠州,516001;广东省惠州市中心人民医院,惠州,516001
摘    要:目的分析小儿病毒性脑膜炎部分病原学情况。方法应用酶联免疫吸附法(ELISA),对92例临床诊断病毒性脑膜炎患儿急性期及恢复期脑脊液进行单纯疱疹病毒(HSV-I、HSV-Ⅱ)、柯萨奇B组病毒(CoxBV)、埃可病毒(ECHO)、EB病毒(EBV)、腺病毒(AdV)及流感病毒(IFV)特异性IgM抗体检测。结果HSV、CoxBV、ECHO、EBV、AdV、IFV病毒感染率分别为8.69%、19.56%、23.91%、3.26%、4.34%、5.43%。结论提示脑脊液中病毒特异性IgM抗体检测可作为早期病原诊断的指标之一。

关 键 词:病毒性脑膜炎  病原学  儿童
文章编号:1672-3619(2006)02-0214-02
收稿时间:2005-04-19
修稿时间:2005-06-27

Survey of Viral Pathogens of the Viral Meningitis in Children
CHEN Wei-ming,LU Yuan-da,LIU Ji-hong. Survey of Viral Pathogens of the Viral Meningitis in Children[J]. Journal Of Tropical Medicine, 2006, 6(2): 214-215
Authors:CHEN Wei-ming  LU Yuan-da  LIU Ji-hong
Abstract:Objective To study the viral pathogens of the viral meningitis in children. Method The specific IgM antibodies of herpes simplex viruses types 1 and 2(HSV-,HSV-),coxsackievirusesB(CoxBV),echoviruses(ECHO),Epsten-Barr viruses (EBV),adenovirus(AdV) and influenza viruses(IFV) were determined with enzyme-linked immunosorbent assay(ELISA) in the cerebrospinal fluid(CSF) from 92 Viral meningitis cases. Result The results showed that specific IgM antibodies to HSV, CoxBV, ECHO, EBV, AdV and IFV were positive, with infection rate of 8.69%,19.56%,23.91%,3.26%,4.34%,and 5.43%, respectively. Conclusion The detections of specific IgM antibodies is one of the ways to make early diagnosis of viral meningitis.
Keywords:viral meningitis  pathogens  children
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