森田疗法与西酞普兰联合治疗强迫症的对照研究

目的：探讨森田疗法与西酞普兰联合治疗强迫症的的疗效及安全性。方法：将56例强迫症患者随机分为观察组和对照组，每组28例。观察组采用森田疗法和西酞普兰治疗，对照组单纯以西酞普兰治疗，疗程2个月。采用Y-BOCS、CGI-SI、HAMD、TESS等量表评定疗效及安全性。结果：在治疗后第4、8周及半年随访时，观察组Y-BOCS、CGI-SI、HAMD等量表评分均显著低于对照组（均P〈0．05），两组不良反应比较差异无显著性（P〉0．05）。结论：森田疗法与西酞普兰联合治疗强迫症的疗效优于单用西酞普兰。

A Controlled Study of Morita Therapy Combined with Citalopram in the Treatment of Obsessive-Compulsive Disorder

Objective : To evaluate the efficacy and safety of Morita therapy combined with citalopram in the treatment of obsessive-compulsive disorder(OCD). Methods: Fifty-six patients with OCD were randomized to two groups. The patients (N=28 ) in observed group were treated with Morita therapy combined with citalopram. The patients (N=28 ) in control group were treated with citalopram alone. The efficacy and safety were assessed with Y-BOCS, CGI-SI , HAMD and TESS scales. Results : The scores of Y-BOCS , CGI-SI and HAMD scales in observed group were significantly lower than that in control group at the end of 4 weeks, 8 weeks and 6 month after the treatment (P<0.05, respectively) . There was no significant difference in side effects between the two groups (P>0.05) . Conclusion: Morita therapy combined with citalopram was more effective than citalopram mono-therapy in the treatment of OCD.