| 小细胞肺癌病人血清癌胚抗原（CEA）动态观察 |
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| 引用本文： | 刘叙仪,熊雪梅.小细胞肺癌病人血清癌胚抗原（CEA）动态观察[J].中国肿瘤临床,1993,20(1):23-27. |
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| 作者姓名： | 刘叙仪 熊雪梅 |
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| 作者单位： | 北京市肿瘤防治研究所，北京市肿瘤防治研究所，北京市肿瘤防治研究所，北京市肿瘤防治研究所，北京市肿瘤防治研究所，贵州省黔南医院肿瘤科 (北京市100034)，(北京市100034)，(北京市100034)，(北京市100034)，(北京市100034) |
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| 摘 要： | 我们对129例小细胞肺癌作了系统血清CEA观察。疗前>5ng/ml者41.9％(54/129),其中>10ng/ml者以广泛期为多(P<0.05)。总有效率(CR PR)以疗前<5ng/ml为优(p<0.05)。疗前CEA增高者,达缓解后均有不同程度下降,且治疗前后CEA均值差别有高度显著性(p<0.001)。生存≥2年者均在疗前CEA<5ng/ml组。但从敏感性、特异性及符合率分析,尚无具体CEA值可作为分期或判断预后的指标。
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| 关 键 词： | 血清 癌胚抗原 肺肿瘤 |
Serial Determinations of Serum Carcinoembryonic Antigen in Small Cell Lung Cancer |
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| Liu Xu-Yi Beijing Institute for Cancer Research.Serial Determinations of Serum Carcinoembryonic Antigen in Small Cell Lung Cancer[J].Chinese Journal of Clinical Oncology,1993,20(1):23-27. |
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| Authors: | Liu Xu-Yi Beijing Institute for Cancer Research |
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| Institution: | Liu Xu-Yi Beijing Institute for Cancer Research |
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| Abstract: | Serum carcinoembrycnic antigen levels were serially determined before,during and after chemothera- py, radiotherapy and maintenance courses in 129 patients with small cell lung cancer. The CEA serum concentration more than 5ng/ml was revealed in 41.9%(54/129) of the patients before treatment. The CEA titers greater than 10ng/ml in patients with extensive or limited disease was 26.5% (20/78) and 11.8% (6/51) respectively (P<0.05). The CEA levels fell in all patients responding to therapy and increased again 1 to 5 months before progression or relapse of the dis- eases in more than half of the patients. All the patients who survived for 2 or more years were in group with pretherapeu- tic CEA concentrations less than 5ng/ml. However, no reasonable conclusions could be drawn from individual CEA levels with regards to stage or prognosis. |
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| Keywords: | Small cell lung cancer Carcinosmbryonic antigen |
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