| 益母草对兔心肌缺血再灌注损伤时氧自由基的影响 |
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| 引用本文： | 郑鸿翱 陈少如. 益母草对兔心肌缺血再灌注损伤时氧自由基的影响[J]. 汕头大学医学院学报, 1997, 10(2): 10-12 |
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| 作者姓名： | 郑鸿翱 陈少如 |
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| 作者单位： | 汕头大学医学院病理生理教研室 |
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| 摘 要： | 本实验观察益母草治疗心肌缺血再灌注损伤过程中氧自由基的变化。结果显示，闪母草能明显抑制血中和心肌组织中的丙二醛的产生，保护超氧化物歧化酶和谷胱甘肽过氧化物酶的活性。表明益母草治疗心肌缺血再灌注损伤的机制可能与益母减轻氧自由基对心肌的损害有关。
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| 关 键 词： | 益母草 氧自由基 再灌注损伤 心肌缺血 植物药 |
Effects of Leonurus Heterophyllus on Oxygen Free Radicals during Myocardial Ischemia Reperfusion Injury in Rabbits |
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| Zheng Hongao,Chen Shaoru,Yin Jun. Effects of Leonurus Heterophyllus on Oxygen Free Radicals during Myocardial Ischemia Reperfusion Injury in Rabbits[J]. Journal of Shantou University Medical College, 1997, 10(2): 10-12 |
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| Authors: | Zheng Hongao Chen Shaoru Yin Jun |
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| Abstract: | The changes of oxygen free radicals in Leonurus Heterophyllus during myocardial ischemia reperfusion injury in rabbits were observed. The results showed that Leonurus Heterophyllus could inhibit the generation of malondialdehyde (MDA), and protect the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX) both in blood and myocardial tissue in evidence (P<0.05~0. 01) as compared with ischemia-reperfusion control group. So it is suggested that Leonurus Heterophyllus has obvious curative effect on myocardial ischemia reperfusion injury. Its mechanism may be relative to allaying myocardial injury induced by oxygen free radicals. |
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| Keywords: | leonurus heterophyllus oxygen free radical myocardium reperfusional injury |
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