| AgNOR检测对宫颈癌预后的意义 |
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| 引用本文： | 李庆菊 刘秀云. AgNOR检测对宫颈癌预后的意义[J]. 肿瘤防治研究, 1996, 23(1): 21-22 |
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| 作者姓名： | 李庆菊 刘秀云 |
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| 作者单位： | 1. 山东省肿瘤防治研究院,250117;
2. 山东省中医院 |
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| 摘 要： | 对73例随访10年以上的宫颈鳞癌进行AgNOR计数分析，发现组织学D级的肿瘤细胞核内AgNOR均值高于组织学Ⅰ级者为5.53± 1.47及4.40±1.34)。10年生存率亦有差异性，AgNOR均值≥5者10年生存率为18%，而<5的10年生存率为46%(P<0.02)。结果表明，AgNOR计数与宫颈鳞癌的组织学分级及临床预后有关。本文认为AgNOR计数可作为一种肿瘤定量指标，对判定肿瘤恶性程度，预测宫颈癌预后具有一定参考价值。
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| 关 键 词： | 宫颈鳞癌；AgNOR；组织学分级；预后 |
Significance of AgNORs in the Progosis of Cervical Squamous Carcinoma |
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| Li QingJu,et al. Significance of AgNORs in the Progosis of Cervical Squamous Carcinoma[J]. Cancer Research on Prevention and Treatment, 1996, 23(1): 21-22 |
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| Authors: | Li QingJu et al |
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| Affiliation: | Shang Dong Tumor &; Institute, JiNan 250117 |
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| Abstract: | AgNORs were analyzed with AgNOR staining in 73 specimens of cervical squamous carcinoma. The results showed that AgNORs of the specimens with Ⅱ histological grade were higher than that of grade Ⅰ, (5. 53±1. 47and, 4. 40±1. 34, respectively), and the patients whose AgNORs were≥5. 0, have a lower 10-year survival rate than the patients whose AgNORs were 5. 0, P0. 02. This indicated that there was a good correlation between AgNORs and histolgical grade or prognosis of the cervical squamous carcinoma,AgNORs could be regarded as a valuable index to judge the malignant grade and the prognosis of cervical squamous carcinoma. |
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| Keywords: | AgNOR cervical squamous carcinoma prognosis hostological grade |
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