| 维生素C微囊缓释片的制备及体外释放度实验 |
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| 引用本文： | 王燕萍,张虹.维生素C微囊缓释片的制备及体外释放度实验[J].中国医院药学杂志,2005,25(11):1023-1024. |
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| 作者姓名： | 王燕萍 张虹 |
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| 作者单位： | 兰州大学第一医院,甘肃,兰州,730000 |
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| 摘 要： | 目的:研制维生素C微囊并制成缓释片剂,评价其体外释放特性.方法:采用溶剂-非溶剂法制备维生素C微囊,制成缓释片剂,采用紫外分光光度法测定其载药量,采用转篮法测定体外释放特性.结果:维生素C缓释片剂,可控制药物释放.结论:该方法工艺简单,可靠,有实用价值.
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| 关 键 词： | 维生素C 微囊 缓释片剂 体外释放度 |
| 文章编号： | 1001-5213(2005)11-1023-02 |
| 收稿时间： | 2004-09-02 |
| 修稿时间： | 2004年9月2日 |
Study on preparation of vitamin C sustained-release tablets and determination of in vitro release rate |
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| WANG Yan-ping,ZHANG Hong.Study on preparation of vitamin C sustained-release tablets and determination of in vitro release rate[J].Chinese Journal of Hospital Pharmacy,2005,25(11):1023-1024. |
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| Authors: | WANG Yan-ping ZHANG Hong |
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| Institution: | The First Affiliated Hospitol of Lanzhou University, Gangsu Lanzhou 730000, China |
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| Abstract: | OBJFCTIVE To prepare vitamin C sustained-release tablets and determine their in vitro release rate. METIHODS Use solvent-non-methods to prepare vitamin C sustained-release tablets, UV method was used to determine its content and the in vitro release rate was determined by rotate basket method RESULTS Vitamin C sustained-release tablets could control release of drug.CONCLUSION The method is simple, reliable and practical |
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| Keywords: | vitamin C microspheres sustained-release tablets in vitro release rate |
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