食管贲门癌根治术后胆石症发病特征及形成机制分析

 目的 回顾分析食管贲门癌根治术后并发胆石症的病例特征,并探讨其可能的形成机制.方法 随访食管贲门癌根治术术后病例,观察术后胆结石的发病情况.结果 共随访171例食管贲门癌根治术后患者,26例(15.2%)出现胆结石,发病率显著高于自然人群(6.6%,P<0.05).胆结石的发病与手术方式有关,颈部吻合组发病率高于胸腔内吻合组,腹部切口组更高.结论 食管贲门癌根治术后有较高的胆石症发病率, 迷走神经的切断及手术方式在胆结石的发生中起着重要作用.

Clinical study of cholelithiasis after radical operation of esophagocardiac carcinoma

Objective To analyse the characteristics and causes of cholelithiasis after radical resection of esophagocardiac carcinoma, Methods Esophagocardiac cancer patients who underwent radical operatiom with a long-term survival were followed up. The incidence of cholelithiasis postoperation was observed and compared.Results A total of 171 patients under going radical esophagocardiaectomy were followed up.15.2% of patients （26/171） developed gallstones,an incidence significantly higher than that in normal people（6.6%, P 〈0.05）. The occurence of gallstones was related to the operatice procedures. The incidence was higher in neck anastomosis group than in intra thoracic anastomosis group, with the highest incidence in laparotomy group. C.ondusions Patients develop cholelithiasis at a high frequency after radical esophagoeardiaectomy. Vagectomy and operation procedures play an important role in the pathogenesis.