| 华山参中2个新酰胺类化合物 |
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| 引用本文： | 娄永,许睿珠,张丽萍,谢治深,张振强,徐江雁,李军,王潘. 华山参中2个新酰胺类化合物[J]. 中草药, 2021, 52(2): 331-334 |
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| 作者姓名： | 娄永 许睿珠 张丽萍 谢治深 张振强 徐江雁 李军 王潘 |
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| 作者单位： | 河南中医药大学中医药科学院, 河南 郑州 450046;河南中医药大学药学院, 河南 郑州 450046 |
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| 基金项目： | 国家重点研发计划-战略性国际科技创新合作专项（2020YFE0201800）；河南省科技攻关项目（202102310183，202102310173）；河南省中医药科学研究专项课题-重大项目（2018ZYZD12） |
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| 摘 要： | 目的 研究华山参(漏斗泡囊草Physochlaina infundibularis干燥根)的化学成分.方法 采用正相硅胶、Sephadex LH-20、HPLC等色谱手段,对华山参药材进行分离纯化,并利用质谱、核磁共振等方法进行化合物结构鉴定.结果 从华山参正丁醇部位初步分离得到3个酰胺类化合物,分别鉴定为N-甲酰基-...
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| 关 键 词： | 华山参 泡囊草属 酰胺类化合物 华山参丁二胺A 华山参丁二胺B N-乙酰基-N-阿魏酰基-1,4-丁二胺 |
| 收稿时间： | 2020-07-17 |
Two new amides from Physochlaina infundibularis |
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| LOU Yong,XU Rui-zhu,ZHANG Li-ping,XIE Zhi-shen,ZHANG Zhen-qiang,XU Jiang-yan,LI Jun,WANG Pan. Two new amides from Physochlaina infundibularis[J]. Chinese Traditional and Herbal Drugs, 2021, 52(2): 331-334 |
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| Authors: | LOU Yong XU Rui-zhu ZHANG Li-ping XIE Zhi-shen ZHANG Zhen-qiang XU Jiang-yan LI Jun WANG Pan |
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| Affiliation: | Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou 450046, China;College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China |
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| Abstract: | Objective To study the chemical constituents of Physochlaina infundibularis. Methods The chemical constituents were isolated by chromatography with silica gel, HPLC, Sephadex LH-20. The structures were identified by MS and NMR analyses. Results Three amides were separated from P. infundibularis and elucidated as trans N-formyl-N-feruloyl-putrescine (1), cis N-acetyl-N-feruloyl-putrescine (2) and trans N-acetyl-N-feruloyl-putrescine (3). Conclusion Compounds 1 and 2 are new compounds, and compound 3 is separated from the genus Physochlaina for the first time. |
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| Keywords: | Physochlaina infundibularis Kuang Physochlaina amides trans N-formyl-N-feruloyl-putrescine cis N-acetyl-N-feruloyl- putrescine trans N-acetyl-N-feruloyl-putrescine |
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